Set Up - also see Screencasts at bottom of page
For USB mic:
1) Plug the microphone and headphones in, then launch Nicecast and Skype.
2) In Nicecast's Source drawer, set the first pop-up to
Audio Device and then select your microphone for the Input Source. This
should be the same device selected in Skype's Audio preferences for
3) Next, open the Effects window, and insert the Application Mixer plugin.